* Supporting Studies
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3 Akazawa N, et al. Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women. Nutr Res. 2012 Oct ;32(10):795-9.
4 Yang YS. Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Phytother Res 2014 Dec;28(12):1770-7.
5 Chandrashekara KT, et al, “Curcumin enhances parental reproductive lifespan and progeny viability in Drosophila melanogaster,” Age, vol. 36, no. 5, 2014
6 Belcaro G, et al. Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Alternative Medicine Review 2010 Dec;15(4):337-44.
7 Thring et al. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complement Altern Med 2009, 9:27 doi:10.1186/1472-6882-9-27.
8 YBundy R, Walker AF, Middleton RW, Booth J. “Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study.” Journal of Alternative & Complementary Medicine. 10(6):1015-8, 2004
9 McFarlin BK, Venable AS, Henning AL, Best Sampson JN, Pennel K, Vingren JL, Hill DW. Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin. BBA Clinical 2016; 5:72-78.
10 Lal B, Kapoor AK, Asthana OP. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res. 1999 Jun;13(4):318-22.
11 Xiao Z, Zhang A, Lin J, Zheng Z, Shi X, Di W, et al. (2014) Telomerase: A Target for Therapeutic Effects of Curcumin and a Curcumin Derivative in Aβ1-42 Insult In Vitro. PLoS ONE 9(7).
12 “Curcumin May Prevent Clogged Arteries.” WebMd.com, 20 July 2009.
13 Khajehdehi P. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr. 2012 Jan;22(1):50-7.
14 Wanwarang W, et al. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol. 2012 Jul 1 ;110(1):40-4.
15 Shin SK, HA TY, McGregor RA, Choi MS. Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. Mol Nutr Food Res. 2011 Nov 7.
16 Kuptniratsaikul V, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med. 2009;15(8):891-897
17 Zaahkouk AMS, et al, “Efficacy of a novel water-soluble curcumin derivative versus sildenafil citrate in mediating erectile function,” International Journal Of Impotence Research, vol. 27, no. 1, pp. 9–15, 2015.
18 Lal B et al. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res 1999 Jun;13(4):318-22.
19 Sanmukhani J, et al. Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial. Phytother Res. 2013 Jul 6.
20 Kim, T., Davis, J., Zhang, A.J., He, X., and Mathews, S.T. (2009) Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biophys. Res. Commun. 388, 377–382.
21 Shoba G, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998 May;64(4):353-6.
22 Tu, Y, et al. Piperine potentiates the hypocholesterolemic effect of curcumin in rats fed on a high fat diet. Exp Ther Med. 2014 Jul;8(1):260-266.
23 Bhutani MK, et al. Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes. Pharmacol Biochem Behav. 2009 Mar;92(1):39-43.
24 Kaur G, et al. Influence of Piperine and Quercetin on Antidiabetic Potential of Curcumin. J Complement Integr Med. 2016 Jun 25.
25 Panahi Y, et al. Effects of Curcuminoids-Piperine Combination on Systemic Oxidative Stress, Clinical Symptoms and Quality of Life in Subjects with Chronic Pulmonary Complications Due to Sulfur Mustard: A Randomized Controlled Trial. J Diet Suppl. 2016;13(1):93-105.
26 Singh S, et al. Piperine Enhances the Protective Effect of Curcumin Against 3-NP Induced Neurotoxicity: Possible Neurotransmitters Modulation Mechanism. Neurochem Res. 2015 Aug;40(8):1758-66.
27 Sehgal A, et al. Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage. Food Chem Toxicol. 2011 Nov;49(11):3002-6.